ThalesNano H-Cube Pro and Phoenix Flow Reactor
One H-Cube Pro and one Phoenix high temperature flow reactors (ThalesNano) for:
- Reaction scale-up in flow
- Homogeneous and heterogeneous flow systems
- High temperature (up to 450 °C) and pressurre (up to 200 bar)
- In-line analytics (e.g. ReactIR) for the study of reaction intermediates and hazardous processes
- Automated column changer for up to 6 independently heated catalyst cartridges
ThalesNano pictures
Vapourtec R-Series Flow Reactor
An R-Series Vapourtec system for liquid flow reactions comprising:
- Fully acid resistant pump modules
- Two piston pumps
- Two peristaltic pumps feeding capable of delivering slurries and gasses
- 4 reactor positions, independently controllable
- Reaction temperature of -70 to 250 °C
- Microreactors
- UV LED reactor for photochemial reactions
- Autosampler and fraction collector
Vapourtec system
fReactor
A fReactor, system containing up to 5 small volume continuous stirred tank reactors connected in series.
- 2 mL individual stage volume - up to 10 mL total volume
- Up to 100 psi pressure
- Works on a common stirrer hotplate
- Good chemical compatibility (reactor materials: PEEK and toughened glass; tubings material: PTFE)
fReactor
Uniqsis FlowSyn and FlowUV
A Uniqsis FlowSyn for liquid flow reactions with:
- 2 high-pressure pump channels with reagent injectors (up to 10 mL/min)
- 1 tubular reaction module (up to 260 °C and 100 bar)
- 1 column heater
A Uniqsis FlowUV for in-line UV-Vis analysis
- Flow cell is transparent PFA reaction tubing
- Dip-probe for batch experiments available
- Can be positioned virtually anywhere in the flow path
- Up to 35 bar at room temperature
- 220-1050nm pulsed Xenon source
- Up to 5 user-selected wavelength real-time monitoring
- Full spectrum mode or multiple fixed wavelength modes
uniqsis
H-Genie Hydrogen Generator
One H-genie high pressure – high flow rate H2 generator for hydrogenation reactions in flow or in batch.
- Pressure range 1-100 bar
- Flow rate range 0.1-1 L/min
- Hydrogen electrochemically generated from DI water
- High purity hydrogen (99.99% at 100 bar)
- Built-in safety features (hydrogen and water leak detectors, internal pressure test, …)
- Monitors hydrogen uptake and logs exportable data
- Different setting options for flow, batch and balloon
H-genie
Synple Capsule Chemistry
One Synple platform (on loan) which allows fully automated, capsule-based synthesis. Synthesise and purify chemicals at the click of a button, by only adding the starting materials, the right solvents and the desired cartridge for the target reaction.
Available reaction cartridges include:
- Reductive amination
- N-Etherocycle formation (SnAP)
- PROTAC formation
- Biotin Tags
- Mitsunobu
- Boc protection
- Boc de-protection
- Deoxyfluorination
- Azide formation
Synple
To find out more about our continuous flow chemistry platforms, contact us at ROAR@imperial.ac.uk
Contact us
Director: Prof Mimi Hii
Email: roar@imperial.ac.uk
The Molecular Sciences Research Hub
Imperial College White City Campus
82 Wood Lane
W12 0BZ London